Plain-English translation of NCT06286189 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 1/2 — A combined trial that checks safety and dosing while also starting to look at whether the treatment works.
This trial is testing whether trazodone, a medication that helps with sleep, can reduce the severity of obstructive sleep apnea — a condition where people stop breathing repeatedly during sleep. Researchers want to understand if this medication can help your body breathe better at night. You would spend two nights sleeping in your home while wearing monitoring equipment, taking either the medication or a placebo pill.
Obstructive sleep apnea is a serious condition that affects many people, and current treatments don't work for everyone. Researchers believe this medication might help reduce breathing interruptions by changing how the body controls breathing during sleep, potentially offering a new treatment option.
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You would participate in two overnight sleep studies in your own home, one week apart. On each night, you would wear monitoring equipment to track your sleep and breathing, then take either the study medication or a placebo pill 30 minutes before bed and sleep naturally without your CPAP machine. Each study night needs at least four hours of good-quality sleep data. The entire study takes about two weeks to complete.
AI-generated summary from trial data · Jun 3, 2026 · Not medical advice
United States