Plain-English translation of NCT06286891 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This is an observational study that follows patients before and after they have pulmonary endarterectomy — surgery to remove chronic blood clots from the lungs that cause high blood pressure in the lungs. The researchers will measure changes in your physical strength, how far you can walk, your lung function, and overall muscle power at several time points: before surgery, when you leave the intensive care unit, when you leave the hospital, and six months later. The goal is to understand which patients struggle most with recovery and what factors predict physical decline during hospitalization.
Many patients who have this lung surgery experience weakness and reduced physical function afterward, but doctors don't have a clear way to predict who will struggle most or how to best support their recovery. This study aims to identify early warning signs of frailty and functional loss so that future patients can receive better support during recovery.
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You will complete several physical and breathing tests at four time points: before your surgery, shortly after leaving the intensive care unit, before you go home from the hospital, and again six months later. These tests include walking for six minutes, standing up and sitting down repeatedly, measuring how hard you can breathe, checking your muscle strength, and answering questions about how fragile or tired you feel. The entire study lasts about six months from your surgery date.
AI-generated summary from trial data · Jun 26, 2026 · Not medical advice
Brazil
Sponsor
University of Sao Paulo General Hospital
Enrollment target
~50 participants
Started
February 2024
Primary completion
September 2025
This trial's estimated completion date has passed — the record may not be fully up to date.
Age range
18 Years and older
Last updated on clinicaltrials.gov in June 2026.
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Central contact
Rafael M Ianotti, PT
Instituto do Coração - Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.