Plain-English translation of NCT06287684 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study is trying to understand why sepsis—a life-threatening condition caused by the body's extreme response to infection—affects different people in different ways. By analyzing blood samples from patients with sepsis, researchers hope to identify distinct immune profiles that could help doctors choose the most effective treatment for each individual patient.
Currently, doctors don't have a way to quickly identify which patients will benefit from specific sepsis treatments, and some patients may even be harmed by standard approaches. This trial exists to create a fast blood test that shows a patient's immune status, so doctors can tailor treatment to each person's unique needs rather than using a one-size-fits-all approach.
You likely qualify if…
You likely don't qualify if…
If you qualify, a researcher will collect a blood sample from you, usually during your stay in the intensive care unit. The blood will be analyzed to determine your immune profile and help doctors understand your sepsis type. Researchers will also review your medical information to compare your case with others in the study. The actual time commitment is minimal—mainly the blood draw itself—though you may be followed as part of routine medical care.
AI-generated summary from trial data · Oct 7, 2026 · Not medical advice
Malta
University of Malta
Enrollment target
~460 participants
Started
September 2023
Primary completion
December 2028
Age range
18 Years and older
Last updated on clinicaltrials.gov in July 2025.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Brendon P. Scicluna, Ph.D.
Mater Dei Hospital, Malta
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.