Plain-English translation of NCT06294106 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Post Traumatic Stress Disorder research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing a new approach called electroencephalogram personalized transcranial magnetic stimulation (eTMS) for people with PTSD. Instead of using a one-size-fits-all approach, this treatment uses a recording of your brain's electrical activity to customize the brain stimulation just for you. Researchers want to see if this personalized method is safe and whether it can help reduce PTSD symptoms.
Current PTSD treatments don't work well for everyone, and standard brain stimulation approaches treat all patients the same way. This trial exists to see if tailoring the treatment to match each person's unique brain activity patterns could make it more effective.
You likely qualify if…
You likely don't qualify if…
You would visit the research center for 2 days of baseline testing before treatment, which includes brain imaging, EEG recordings, sleep studies, and behavioral tasks. Then you would receive the personalized brain stimulation treatment (or a sham treatment, depending on which group you're assigned to). Finally, you would return for 2 more days of testing after treatment to see if anything has changed. The entire study involves non-invasive tests—no surgery or medications are involved.
AI-generated summary from trial data · Jul 8, 2026 · Not medical advice
United States
Sponsor
Virginia Polytechnic Institute and State University
Collaborators
Wave Neuroscience
Enrollment target
~20 participants
Started
June 2024
Primary completion
June 2028
Age range
18 Years – 65 Years
Last updated on clinicaltrials.gov in July 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Jessica Florig, MPH
Virginia Polytechnic Institute and State University
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.