Plain-English translation of NCT06295159 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 2 — Testing in a bigger group (up to a few hundred people) to see if the treatment actually works and is still safe.
This trial is testing whether giving immunotherapy medications like before surgery, tailored to your tumor's specific characteristics, can help people with advanced melanoma. The study uses the body's own immune system to fight cancer by giving medications intravenously (through an IV) before you have surgery to remove the melanoma, and then continues treatment afterward.
Standard treatment for advanced melanoma usually involves surgery, but researchers want to see if giving the medication first—before surgery—can shrink tumors and improve how well the treatment works overall. By matching the medication to your tumor's biomarkers, doctors hope to give you the most effective option.
You likely qualify if…
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You would receive two cycles of immunotherapy medication through an IV infusion, spaced four weeks apart, before your melanoma surgery. After surgery, you would continue with additional medication cycles as part of the treatment plan. The study involves clinic visits for infusions, monitoring, and follow-up care to track how well the treatment works and any side effects you experience.
AI-generated summary from trial data · Jun 15, 2026 · Not medical advice
United States