Testing a cholesterol medication to prevent heart attacks and strokes

This trial is testing whether Repatha®, a cholesterol-lowering medication, helps prevent heart attacks and strokes when added to standard heart disease treatment. Researchers will follow about 7,000 Chinese patients who have already been diagnosed with heart or blood vessel disease and compare those taking the medication alongside their usual care with those receiving usual care alone. The study will track whether this medication reduces serious heart-related events over time.

Many people with heart disease continue to have heart attacks and strokes even while taking standard treatments. This study wants to understand whether this medication can provide additional protection by lowering cholesterol even further, especially for patients in China where real-world treatment patterns may differ from other countries.