Plain-English translation of NCT06296810 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Parkinson Disease research guide →This trial is testing a feature called adaptive deep brain stimulation (aDBS) using the Percept brain stimulator in people with Parkinson's disease who already have this device implanted. Researchers want to see if the device can automatically detect and respond to changes in brain activity that happen during exercise, and whether this smart adjustment can help reduce Parkinson's symptoms that get worse when you exercise.
Exercise can temporarily worsen Parkinson's symptoms in some people, even though exercise is generally helpful for the disease. This trial exists to see whether a device that learns and adapts in real time can counteract this problem, making it safer and easier for people with Parkinson's to stay active.
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As a participant, you would work with researchers to perform exercise while they monitor the brain signals from your implanted device. The study team will test whether the device can automatically detect when Parkinson's symptoms start to worsen during exercise and then adjust its stimulation settings in response. The trial involves a small group of about 10 people and is currently recruiting participants.
AI-generated summary from trial data · Jun 19, 2026 · Not medical advice
United States
Sponsor
University of Colorado, Denver
Enrollment target
~10 participants
Started
September 2024
Primary completion
December 2025
This trial's estimated completion date has passed — the record may not be fully up to date.
Age range
20 Years – 70 Years
Last updated on clinicaltrials.gov in March 2025.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Pamela David Gerecht, PhD
University of Colorado, Denver
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.