Plain-English translation of NCT06297200 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
Researchers are testing a treatment called Low-Intensity Focused Ultrasound (LIFU)—a type of sound wave therapy—to see if it can help reduce pain, drug cravings, and anxiety symptoms. This study focuses on people who have chronic back pain, are in treatment for opioid addiction, and experience an anxiety disorder. The goal is to understand whether this non-invasive sound wave approach might offer relief for patients dealing with all three of these conditions at once.
Many people struggle with chronic pain, opioid addiction, and anxiety at the same time, and current treatments don't always work well for everyone. Researchers believe this new treatment approach using focused sound waves might help address multiple symptoms in a way that existing therapies cannot.
You likely qualify if…
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You would visit the study site multiple times to receive either the focused ultrasound treatment or a sham (placebo) treatment—you won't know which one you're getting. Before and after each treatment session, you'll answer questions and complete assessments about your pain levels, cravings for opioids, and anxiety symptoms. The study team will use these measurements to see whether the sound wave treatment helps reduce your symptoms compared to the placebo.
AI-generated summary from trial data · Jun 11, 2026 · Not medical advice
United States
Sponsor
Virginia Polytechnic Institute and State University
Collaborators
Salem VA Medical Center, Washington DC VA Medical Center
Enrollment target
~25 participants
Started
December 2024
Primary completion
October 2026
Age range
18 Years – 65 Years
Last updated on clinicaltrials.gov in November 2025.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Jessica Florig, MPH
Virginia Polytechnic Institute and State University
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.