Plain-English translation of NCT06297278 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This is a research study for teenagers ages 14–17 that explores whether exercise can help improve how your brain handles fear and anxiety. Researchers want to understand whether a moderate-intensity exercise session can change brain activity and boost natural chemicals in your brain (called endocannabinoids) that help regulate fear. If this works, it could lead to better treatments for anxiety disorders in young people.
Many teenagers develop anxiety disorders, and current treatments don't work well enough for everyone. Scientists have discovered new information about how the adolescent brain learns and manages fear, but haven't yet figured out how to turn this knowledge into better therapies. This study aims to bridge that gap by testing whether exercise — a simple, accessible intervention — could naturally boost the brain's ability to overcome anxiety.
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You would visit the research site for study visits with a parent or guardian. During the study, you would either do a moderate-intensity exercise session (like using a stationary bike) or a control activity (coloring), and researchers would measure your brain activity and take blood samples to study how your brain responds. The exact number and length of visits will be explained during the enrollment process, but the study involves brain imaging and standard laboratory tests.
AI-generated summary from trial data · Jun 2, 2026 · Not medical advice
United States