Plain-English translation of NCT06297291 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Hypertension research guide →This trial is testing the Paradise System, an ultrasound-based procedure designed to treat high blood pressure by calming overactive nerves surrounding the kidney blood vessels. In some people, these nerves become overactive and contribute to dangerously high blood pressure. The Paradise System uses heat delivered through a thin catheter to disable this nerve activity and help lower blood pressure.
Many patients continue to struggle with high blood pressure even while taking multiple medications. This study exists to see whether this treatment can offer another option for people whose blood pressure remains too high despite their current medicines.
You likely qualify if…
You likely don't qualify if…
If you qualify, you will receive the ultrasound renal denervation procedure and then be followed by the study team for 5 years. You'll have regular clinic visits, measure your blood pressure at home using a monitor provided by the study, and complete surveys about your quality of life, health, sleep, and mood. The study team will track how your blood pressure changes and how you feel over time.
AI-generated summary from trial data · Jun 25, 2026 · Not medical advice
United States