Plain-English translation of NCT06302803 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Obesity research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This study is testing a modified intermittent eating strategy to help people with obesity lose weight and improve their heart health. The approach combines eating during a limited time window on some days with very low-calorie eating on other days. Researchers will compare this strategy to traditional calorie restriction and to usual care over one year to see which works best.
While calorie restriction is known to help with weight loss, newer eating approaches like intermittent fasting have become popular but haven't been thoroughly tested in scientific studies. This trial exists to find out whether combining time-restricted eating with fasting days is an effective and safe way to help people lose weight and reduce their risk of heart disease.
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If you join this study, you will be randomly assigned to one of three groups: a modified intermittent eating group (eating in an 8-hour window 5 days a week and eating very little on 2 fasting days), a traditional calorie-restriction group (eating 1200–1800 calories daily), or a usual care control group. You will follow your assigned approach for 12 months, with regular check-ins to track your weight, blood pressure, cholesterol, and other health markers.
AI-generated summary from trial data · Jun 16, 2026 · Not medical advice
China
Sponsor
Nanfang Hospital, Southern Medical University
Enrollment target
~225 participants
Started
April 2024
Primary completion
December 2026
Age range
18 Years – 75 Years
Last updated on clinicaltrials.gov in June 2024.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Huijie Zhang, MD. PhD.
Department of Endocrinology and Metabolism, Nanfang Hospital, Southern Medical University
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.