Plain-English translation of NCT06311123 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Ulcerative Colitis research guide →Researchers want to understand how ozanimod works to treat ulcerative colitis by studying immune cells in your blood and intestines. This trial collects samples before you start the medication and again 6 months later to see what changes happen. By studying these cellular changes, doctors hope to better understand why this treatment helps some patients.
Ulcerative colitis causes painful inflammation in the colon, but doctors don't fully understand exactly how newer medications like ozanimod calm down that inflammation. This study aims to fill that gap by closely examining the immune system's response to this medication, which could help doctors predict who will benefit most and improve treatment in the future.
You likely qualify if…
You likely don't qualify if…
You will have two study visits: one before starting the medication and another 6 to 8 months after you begin treatment. At each visit, researchers will draw blood samples and collect small tissue samples from your intestines during a scheduled colonoscopy. All samples are frozen and stored for laboratory analysis to examine your immune cells. The study involves about 10 participants total and requires close coordination with your regular gastroenterologist.
AI-generated summary from trial data · Jun 2, 2026 · Not medical advice
United States