Plain-English translation of NCT06313801 on ClinicalTrials.gov ↗ · Source last updated · Translation generated ·
Phase 2 — Testing in a bigger group (up to a few hundred people) to see if the treatment actually works and is still safe.
This trial is testing whether combining standard chemotherapy drugs (FLOT, which includes , , , and ) with a newer procedure called PIPAC—where chemotherapy is delivered directly into the abdomen through a small scope—works better than chemotherapy alone. The study involves people with stomach cancer that has spread to the inner lining of the abdomen (called peritoneal carcinomatosis), which is a serious condition.
Stomach cancer that spreads to the abdominal lining is very difficult to treat, and outcomes remain poor with standard chemotherapy alone. Researchers believe that delivering medication directly to the affected area via this minimally invasive procedure may improve survival and control the cancer better than chemotherapy given through the veins.
You likely qualify if…
You likely don't qualify if…
If you qualify, you will first undergo a small diagnostic scope procedure (laparoscopy) to confirm the extent of cancer in your abdomen. Then you will be randomly assigned to receive either standard chemotherapy alone, or the same chemotherapy combined with PIPAC treatments (where chemotherapy is infused directly into your abdomen during a minimally invasive procedure). You will receive chemotherapy every 2 weeks for 6 cycles total, with visits to the hospital for infusions and regular blood tests and scans to monitor your response.
AI-generated summary from trial data · Jun 13, 2026 · Not medical advice
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