Plain-English translation of NCT06314477 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This study is testing whether a CPAP machine—a device that gently pushes air through your nose to keep your airway open while you sleep—can help improve asthma control in people with severe asthma that hasn't responded well to standard treatments. Researchers have noticed that many people with severe asthma also have obstructive sleep apnea (a condition where breathing stops and starts during sleep), and treating the sleep apnea might help their asthma. This trial will compare people who use the CPAP machine against those who receive standard asthma care alone.
Small studies have shown that CPAP treatment may help people with mild-to-moderate asthma, but no one has studied whether it works for people with severe, uncontrolled asthma. This research aims to fill that gap and see if treating sleep apnea can be a new way to help people whose asthma isn't improving with current medications.
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You will be randomly assigned to either receive standard asthma care (including lifestyle and dietary advice) or standard care plus CPAP treatment. If you receive the CPAP machine, you'll use it at night while sleeping. The study lasts 12 months, and you'll have check-in visits at 1 month, 6 months, and 12 months to see how your asthma is responding and how well the CPAP is working for you.
AI-generated summary from trial data · Jun 5, 2026 · Not medical advice
Spain
Sponsor
Hospital Clinic of Barcelona
Enrollment target
~138 participants
Started
December 2023
Primary completion
December 2026
Age range
18 Years and older
Last updated on clinicaltrials.gov in December 2025.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Mireia Dalmases, MD
Hospital Clinic
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.