Testing a new continuous kidney cleaning device for dialysis patients

Plain-English translation of NCT06314503 on ClinicalTrials.gov ↗ · Source last updated July 2025 · Translation generated June 2026 · How we translate trials

This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.

This is one of the first times this treatment has been tested in people.

What is this trial?

This trial is testing a new medical device called WEAKID that may improve peritoneal dialysis — a form of kidney treatment that cleans waste from your blood using your abdominal lining as a filter. The device works by continuously circulating and regenerating the cleaning fluid, which could remove more waste and reduce some of the common problems patients face with standard dialysis.

Current peritoneal dialysis has limitations: it doesn't remove enough waste products from the blood, requires frequent fluid changes, and can damage the abdominal lining over time due to high sugar concentrations in the cleaning fluid. This new treatment is designed to address these problems and help patients stay healthier longer on dialysis.

Do you qualify?

You likely qualify if…

you are 18 years of age or older
you have been on peritoneal dialysis for at least 3 months
your dialysis catheter (tube) is working well with no replacements in the past month
you have not had a dialysis-related infection in the 8 weeks before enrollment
you have previously used or can use Extraneal dialysis fluid without allergic reactions

You likely don't qualify if…

you are unable to understand the study information or give informed consent
you have had a recent infection related to your dialysis (exit-site, tunnel, or peritoneal infection) in the past 8 weeks
you have problems with your dialysis catheter or mechanical issues in the past month
you have a known allergy to cornstarch, icodextrin, maltose, or isomaltose, or you have glycogen storage disease
you have a serious medical condition that could make participation unsafe, or a life expectancy of less than 3 months

What participation looks like

You would receive six treatment sessions with the WEAKID device spread over two weeks while continuing your regular dialysis care. Each session involves using the new device through your existing dialysis catheter, allowing researchers to monitor how safely and effectively it works for you. You would attend study visits to have your blood work checked and discuss any side effects or concerns with the research team.

Testing a new continuous kidney cleaning device for dialysis patients

What is this trial?

Do you qualify?

What participation looks like

Trial locations(3 sites)