Plain-English translation of NCT06318416 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 1 — Testing in a small group (usually 20–80 people) to find a safe dose and watch for side effects.
This trial is testing whether a simple urine test can help doctors find the best dose of rifampin — a key tuberculosis medicine — for each person. Researchers will check your urine and blood at different times to see how your body is absorbing the medication, and if needed, they'll adjust your dose to make sure you're getting enough to fight the infection effectively.
Not everyone's body absorbs tuberculosis medicine the same way, which means some people may not get enough of the medication to cure their infection. This trial is trying to figure out if a quick urine test can help doctors personalize doses so that every patient gets the right amount of treatment.
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You will visit the hospital regularly to provide urine and blood samples while taking your tuberculosis medicine. Depending on which group you're assigned to, your dose will be checked and possibly adjusted either 2 weeks or 3 weeks after you start treatment. The study team will monitor your health throughout your treatment with blood tests and stool samples to understand how your body is handling the medication.
AI-generated summary from trial data · Jun 3, 2026 · Not medical advice
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