Recruiting

3D imaging guidance during prostate cancer surgery to improve outcomes

Plain-English translation of NCT06318559 on ClinicalTrials.gov ↗ · Source last updated March 2024 · Translation generated July 2026 · How we translate trials

This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.

What is this trial?

This trial is testing whether artificial intelligence 3D imaging technology can improve robotic prostate cancer surgery. Surgeons will use special 3D visualization to see exactly where the cancer is during surgery, which may help them remove it more completely while protecting important nerves that control urination and sexual function. Half of participants will receive surgery with this 3D guidance, and half will receive standard surgery without it.

Prostate cancer is difficult to see during surgery with the naked eye, especially in earlier stages, which means surgeons sometimes cannot tell if they've removed all the cancer or accidentally damaged important nerves. This trial aims to determine whether 3D imaging technology can help surgeons be more precise, leading to better cancer outcomes and fewer side effects.

Do you qualify?

You likely qualify if…

you are a man over 40 years old
you have been diagnosed with prostate cancer that shows signs of spreading outside the prostate on imaging
you have had an MRI scan of your prostate before enrollment
you are in good enough health to undergo prostate removal surgery and have a life expectancy of at least 5 years
you are motivated to preserve sexual function and had sexual activity before diagnosis
you are willing to attend follow-up visits and provide medical data

You likely don't qualify if…

you have very high PSA levels (over 100 ng/ml) at diagnosis
you cannot have an MRI due to a pacemaker or other implant, or claustrophobia
you have serious uncontrolled infections or other medical conditions
you have dementia or psychiatric illness that would prevent you from understanding the study or following instructions
you have rare types of prostate cancer or already have large lymph node involvement

What participation looks like

If you qualify, you will be randomly assigned to receive either standard robotic prostate cancer surgery or the same surgery with 3D imaging guidance to help your surgeon. You will undergo the planned surgery and then return for follow-up visits over time to check for cancer recurrence and to assess your urinary and sexual function. The research team will collect your medical information and imaging results to compare how well the two approaches work.

AI-generated summary from trial data · Jul 21, 2026 · Not medical advice

Trial locations(2 sites)

Italy

Fondazione del Piemonte per l'Oncologia-IRCCS Candiolo, Candiolo, Turin

AOU san Luigi Gonzaga, Orbassano, Turin