Plain-English translation of NCT06320990 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 1 — Testing in a small group (usually 20–80 people) to find a safe dose and watch for side effects.
This trial is testing whether tamoxifen, a medication that blocks certain hormones in the body, can help shrink or stop the growth of pancreatic cysts. Researchers believe this medication may prevent these cysts from becoming cancer, potentially sparing some patients from needing surgery. This is a small pilot study designed to see if this approach is feasible and effective.
Pancreatic cysts that could become cancer currently have only one treatment option: surgery. Because these cysts seem to be driven by hormones in the body, doctors want to test whether blocking those hormones with this medication could be an alternative or delay the need for surgery.
You likely qualify if…
You likely don't qualify if…
If you join this study, you would take one tablet of the medication by mouth once daily for up to 6 months. During this time, you would have periodic imaging scans (like MRI) to measure whether your cyst is shrinking, staying the same, or growing. The study involves up to 15 participants total and is designed to test whether this treatment approach works and is tolerable, paving the way for a larger future study.
AI-generated summary from trial data · Jun 15, 2026 · Not medical advice
United States