Plain-English translation of NCT06322056 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
The EXCELSIOR-CKD study is testing whether treating blood pressure and cholesterol more aggressively — aiming for lower targets than standard care — can help protect your kidneys if you have advanced chronic kidney disease. You would be randomly assigned to one of four treatment groups, each with different targets for blood pressure and cholesterol levels. The goal is to find out which approach works best at slowing or preventing further kidney damage.
Doctors know that high blood pressure and high cholesterol can damage kidneys, but they're not certain whether aiming for even lower targets than usual would provide extra protection. This study will help answer that question for people with advanced kidney disease.
You likely qualify if…
You likely don't qualify if…
You would visit the clinic regularly over approximately 3 years for blood pressure checks, blood work, and medication adjustments. Depending on which group you're assigned to, you'd take medications aiming for either stricter or standard targets for blood pressure (below 120 or below 140 mmHg) and cholesterol (below 70 or below 100 mg/dL). The research team would monitor your kidney function and overall health throughout the study to see if the more intensive approach helps protect your kidneys better.
AI-generated summary from trial data · Jun 2, 2026 · Not medical advice
South Korea