Plain-English translation of NCT06323018 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing whether a technique called remote ischemic preconditioning (RIPC) can protect your heart, kidneys, and brain during cemented hip replacement surgery. The procedure involves briefly reducing blood flow to your arm using a special cuff before surgery — similar to getting your blood pressure checked. Researchers believe this may prepare your body to better handle the stress of surgery.
Cemented hip replacement, while very effective for severe arthritis, can sometimes cause a complication called bone cement implantation syndrome that temporarily reduces oxygen and blood pressure and may damage vital organs. This trial is testing whether the protective technique can prevent these complications and keep your organs safer during surgery.
You likely qualify if…
You likely don't qualify if…
About one hour before your hip replacement surgery, you will receive either the protective procedure or a sham (fake) procedure. The protective procedure involves placing a blood pressure cuff on your arm and briefly inflating it to reduce blood flow, then releasing it — repeated four times. After that, you will proceed with your regular hip replacement surgery. Researchers will then monitor you after surgery to measure how well your heart, kidneys, and brain are functioning.
AI-generated summary from trial data · Jun 9, 2026 · Not medical advice
Estonia
Sponsor
University of Tartu
Enrollment target
~200 participants
Started
March 2024
Primary completion
March 2026
This trial's estimated completion date has passed — the record may not be fully up to date.
Age range
65 Years – 90 Years
Last updated on clinicaltrials.gov in April 2024.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Kaspar Tootsi, PhD
University of Tartu
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.