Plain-English translation of NCT06323278 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Parkinson Disease research guide →This study is testing whether cognitive stimulation—a type of brain training program—works differently for people with Parkinson's disease who carry a specific genetic change (called a GBA mutation) compared to those without this genetic change. Researchers will compare how well the brain training helps each group improve their thinking and memory skills.
Some people with Parkinson's disease experience cognitive decline, meaning their thinking and memory abilities can get worse over time. This study wants to understand whether brain training can help slow or prevent this decline, and whether certain genetic differences affect how well the treatment works for different patients.
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You will undergo cognitive testing (thinking and memory evaluations) to understand your baseline abilities, have genetic testing completed, and then participate in a cognitive stimulation program—specialized brain training exercises—as part of your regular Parkinson's care. Researchers will track how the training affects your cognitive abilities and any changes in mood or behavior over time, comparing your results to other Parkinson's patients without the GBA genetic mutation.
AI-generated summary from trial data · Jul 10, 2026 · Not medical advice
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