Plain-English translation of NCT06323876 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study is testing whether advanced CT scans of the lungs — combined with blood tests and other measurements — can better predict how idiopathic pulmonary fibrosis (IPF) will progress in each patient. Right now, doctors use a simple breathing test to monitor the disease, but it doesn't catch subtle changes. The researchers hope that detailed computer analysis of lung scans, along with blood markers, will give a clearer picture of disease activity and how well treatments are working.
IPF is a serious lung disease that causes scarring, and despite two available medications, it remains life-threatening. The current standard breathing test is limited and doesn't detect early changes well. This study exists to find better tools for predicting which patients will decline faster and for measuring whether new treatments are actually helping.
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You would be part of an ongoing study at either the University of Virginia or University of Chicago. Participants have CT scans of their lungs taken at baseline and at follow-up visits, along with breathing tests and blood work to measure lung function and disease markers. Your existing medical scans and blood samples that were already collected may be used, and you may have additional scans and blood draws during the study to help researchers understand how the disease changes over time.
AI-generated summary from trial data · Jun 3, 2026 · Not medical advice
United States
Sponsor
University of Virginia
Collaborators
National Heart, Lung, and Blood Institute (NHLBI)
Enrollment target
~160 participants
Started
June 2024
Primary completion
May 2028
Age range
40 Years – 101 Years
Last updated on clinicaltrials.gov in August 2024.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Roselove Nunoo-Asare
Division of Pulmonary and Critical Care
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.