Plain-English translation of NCT06325202 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Diabetes Mellitus, Type 1 research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This study is testing whether using a hybrid closed-loop insulin device—a smart pump that automatically adjusts insulin based on your blood sugar readings—can help restore your ability to feel and respond to low blood sugar episodes. Some people with long-standing type 1 diabetes lose this warning ability over time. The trial also tests whether adding educational programs that teach coping skills can further improve awareness and reduce severe low blood sugar events.
People with type 1 diabetes who have had the disease for many years sometimes lose the ability to feel when their blood sugar is dangerously low, which puts them at much higher risk of serious complications. We don't yet know whether using modern insulin technology and/or structured education can help restore this warning system.
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You will be randomly assigned to one of several groups that either start with a hybrid closed-loop device, start with educational classes about managing low blood sugar, or both over a 24-month period. You will wear a continuous glucose monitor and attend regular study visits where researchers will test your body's response to low blood sugar using a controlled lab procedure. Throughout the study, you'll work with the research team to track how well you're doing and whether your awareness of low blood sugar improves.
AI-generated summary from trial data · Jun 25, 2026 · Not medical advice
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