Plain-English translation of NCT06325488 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This research study is examining how Fabry disease affects the kidneys using advanced imaging technology. Fabry disease is a rare genetic condition where harmful substances build up in cells throughout the body, including the kidneys, causing progressive damage over time. Researchers want to understand exactly how this damage happens so they can develop better treatments and know when patients need help most.
Although doctors know that Fabry disease damages the kidneys, they don't fully understand the exact mechanisms driving this damage or how to best predict and treat it. This study aims to fill that gap by using advanced imaging to see what's happening inside the kidney tissue, which could help guide future treatment decisions.
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Participants will undergo advanced imaging scans (MRI) to examine their kidney tissue in detail. The study compares three groups: people with Fabry disease and kidney damage, people with Fabry disease with normal kidneys, and healthy volunteers with no Fabry disease. You would visit the research center for imaging sessions and possibly provide blood or urine samples to help researchers understand the relationship between what they see on the scans and how well your kidneys are functioning.
AI-generated summary from trial data · Jun 18, 2026 · Not medical advice
Denmark
Sponsor
Caroline Michaela Kistorp
Collaborators
Sanofi
Enrollment target
~60 participants
Started
June 2024
Primary completion
March 2026
This trial's estimated completion date has passed — the record may not be fully up to date.
Age range
18 Years and older
Last updated on clinicaltrials.gov in April 2025.
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Central contact
Caroline M Kistorp, Professor
Rigshospitalet, Denmark
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.