Plain-English translation of NCT06325644 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing whether a ketogenic diet—a diet very low in carbohydrates and high in healthy fats—can help slow down polycystic kidney disease in people whose kidneys are at higher risk of declining quickly. Researchers will track how the diet affects kidney function, kidney size, and protein in your urine over one year. You'll work with a diet team to follow the plan and have regular check-ins with blood tests and imaging to see how you're doing.
Polycystic kidney disease can progress to kidney failure, especially in people with certain risk factors. Doctors are exploring whether dietary changes like the ketogenic diet might help delay this progression and give patients more time before needing dialysis or a transplant.
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You will follow a ketogenic diet for one year, working closely with the research team's diet specialists to plan your meals and stay on track. You'll have three study visits (at the start, at 6 months, and at 1 year) where you'll get blood tests, provide urine samples, and have an MRI scan to measure your kidney size and function. Between visits, the diet team will check in with you to make sure the plan is working and answer any questions.
AI-generated summary from trial data · Oct 12, 2026 · Not medical advice
United States