Plain-English translation of NCT06326294 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing two different ways to treat abnormal cervical cells in women living with HIV. One approach uses heat to destroy the abnormal tissue (thermal ablation), while the other uses a wire loop to remove the tissue (LEEP). The study wants to see which method works better at eliminating the virus and preventing cervical cancer.
Women with HIV are at higher risk for cervical cancer because of their weakened immune systems. Doctors need to know which treatment works better to get rid of the virus and abnormal cells, so they can protect women's health more effectively.
You likely qualify if…
You likely don't qualify if…
If you join this study, you will be randomly assigned to receive either the thermal ablation treatment or the LEEP procedure. You will have biopsies taken before the thermal ablation treatment to check the tissue, while the LEEP group will have the procedure without routine biopsies. The study will follow you after treatment to see how well each method works and monitor for any side effects or pain.
AI-generated summary from trial data · Jun 3, 2026 · Not medical advice
Mozambique
Instituto Nacional de Saúde, Mozambique
Collaborators
M.D. Anderson Cancer Center
Enrollment target
~4,844 participants
Started
April 2024
Primary completion
September 2027
Age range
25 Years – 49 Years
Sex
Female only
Last updated on clinicaltrials.gov in May 2024.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Edna Viegas, MD, PhD
Instituto Nacional de Saúde, Mozambique
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.