Plain-English translation of NCT06326892 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study is comparing two surgical methods for removing rectal cancer: one where the tissue is extracted through the anus (called Natural Orifice Specimen Extraction, or NOSE), and one using a traditional approach through an abdominal incision. Researchers want to understand which method leads to better recovery, less pain, and improved quality of life for patients with low rectal cancer.
Most research on this newer extraction technique has focused on colon cancer, not rectal cancer. Doctors need to know whether this treatment works well specifically for rectal cancer patients and whether it truly offers the pain relief and faster recovery that early studies suggest.
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This is a retrospective study, meaning researchers will review medical records of patients who already had rectal cancer surgery between 2017 and 2023. You would not be undergoing a new procedure — instead, researchers will compare the recovery outcomes (pain levels, bowel function, cosmetic satisfaction, and emotional wellbeing) between patients who had the newer extraction method and those who had the traditional method.
AI-generated summary from trial data · Jun 3, 2026 · Not medical advice
Italy
Enrollment target
~350 participants
Started
July 2023
Primary completion
May 2024
This trial's estimated completion date has passed — the record may not be fully up to date.
Age range
18 Years and older
Last updated on clinicaltrials.gov in June 2024.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Annalisa Maroli, PhD
IRCCS Huamanitas Research Hospital
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.