Plain-English translation of NCT06327451 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 2 — Testing in a bigger group (up to a few hundred people) to see if the treatment actually works and is still safe.
This trial is testing whether atorvastatin, a medication commonly used to lower cholesterol, can help fight glioblastoma—a serious and aggressive brain tumor—when combined with standard chemotherapy and radiation. Researchers believe this medication may slow tumor growth by blocking a pathway that allows cancer cells to progress. The study will track how well this combination works and how safe it is over one year.
Even with current best treatments, glioblastoma remains very difficult to treat, with patients surviving only about 14 months on average. Recent research suggests this medication might have anti-cancer properties that could help stop tumor growth, so researchers want to see if adding it to standard treatment could help patients live longer.
You likely qualify if…
You likely don't qualify if…
After surgery and standard brain tumor treatment begins, you will take one tablet of the medication by mouth each night for the duration of the study. You will have regular follow-up visits over 52 weeks that include MRI scans to check how your tumor is responding and blood tests to monitor your health and safety. The study team will track whether your tumor shrinks, stays stable, or grows, and watch for any side effects from the combined treatment.
AI-generated summary from trial data · Oct 7, 2026 · Not medical advice
China