Plain-English translation of NCT06329726 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Parkinson Disease research guide →This is an observational study that tracks how deep brain stimulation (a surgical treatment that uses electrical pulses to help control Parkinson's symptoms) affects thinking, memory, and mood over the long term. Researchers will compare people who have received this brain stimulation surgery with people who are managing their Parkinson's with medications alone, following both groups for 5 years to see how their cognitive and behavioral health changes.
While deep brain stimulation can help reduce movement problems in Parkinson's disease, doctors don't have enough information about how it affects thinking and behavior over many years. This study aims to fill that gap so patients and doctors can make better-informed decisions about whether this treatment is right for them.
You likely qualify if…
You likely don't qualify if…
You will visit the research clinic for an initial assessment and then return for follow-up visits once a year for 5 years. At each visit, you'll complete cognitive tests (like memory and thinking exercises), answer questionnaires about your mood and behavior, and undergo standardized clinical assessments. The researchers will use this information to compare how people who received brain stimulation surgery fare over time compared to those using medication alone.
AI-generated summary from trial data · Jun 10, 2026 · Not medical advice
Italy