Plain-English translation of NCT06332391 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing a new way to use pacemakers that are already in place for heart failure patients. Instead of just regulating your heartbeat, the device will pace your heart to follow the same rhythm pattern your heart would naturally have during exercise — done safely while you're resting. Researchers hope this gentle, repeated pacing will help strengthen your heart muscle and improve your ability to exercise over a six-week period.
Many people with weakened hearts struggle to exercise and feel tired, even with current medications. This trial exists to see whether teaching your heart to follow an exercise-like pattern — without you having to actually exercise — might help your heart recover strength and improve your daily life.
You likely qualify if…
You likely don't qualify if…
You will first come in for baseline testing, which includes blood work, heart imaging, walking tests, and questionnaires about your symptoms and quality of life. Then, three times per week for six weeks, you will receive either the special pacing treatment or a sham (placebo) pacing session — you won't know which one you're getting. During the six weeks, you'll wear an activity monitor to track your daily movement. At weeks 2, 4, and 6, you'll return for follow-up visits to see how you're responding.
AI-generated summary from trial data · Aug 6, 2026 · Not medical advice
United States