Plain-English translation of NCT06336941 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing whether intraoral ultra-high frequency ultrasound — a special imaging technique that uses sound waves — can help doctors better understand oral cancers by measuring their depth and thickness. Unlike biopsies, this ultrasound method is non-invasive, meaning it doesn't require cutting into your tissue. The study aims to see if this imaging tool can support clinical decisions for patients with oral squamous cell carcinoma.
Doctors currently rely on clinical examination and biopsies to diagnose and plan treatment for oral cancers, but these methods don't always show what's happening beneath the surface. This trial exists to determine whether the new ultrasound technique could provide a simpler, repeatable, and less invasive way to measure tumor size and depth, which are important for treatment planning.
You likely qualify if…
You likely don't qualify if…
If you qualify, you will undergo an intraoral ultrasound scan using a specialized probe that operates at 70 MHz frequency. This scan will be performed to evaluate the depth of invasion and thickness of your tumor. The procedure is non-invasive and does not involve surgery or biopsy — the probe is placed inside your mouth to capture ultrasound images of the lesion.
AI-generated summary from trial data · Jun 16, 2026 · Not medical advice
Italy
Sponsor
University of Pisa
Enrollment target
~400 participants
Started
June 2018
Primary completion
December 2025
This trial's estimated completion date has passed — the record may not be fully up to date.
Age range
18 Years and older
Last updated on clinicaltrials.gov in February 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Rossana Izzetti, DDS, PhD
University of Pisa
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.