Plain-English translation of NCT06338683 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 3 — Testing in thousands of people, comparing the treatment against what doctors currently use. This is the last big step before approval.
This trial is testing whether olanzapine, a medication commonly used to treat psychiatric conditions, can help people with advanced cancers live longer when added to their standard cancer treatment. Researchers believe the medication may help by reducing weight loss and improving overall health during chemotherapy. Half of participants will receive the medication along with nutritional advice and standard cancer treatment, while the other half will receive nutritional advice and standard cancer treatment alone.
People with advanced cancers often experience severe weight loss and poor nutrition during chemotherapy, which can affect their survival and quality of life. Researchers want to see whether this medication might help prevent weight loss and improve outcomes when combined with standard cancer care.
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If you join this study, you will be randomly assigned to one of two groups. One group will take the medication by mouth daily along with nutritional advice and standard cancer treatment; the other group will receive nutritional advice and standard cancer treatment only. Throughout the study, you will have regular follow-up visits to measure your weight, check your blood work, and assess how you are feeling. The study will track your cancer progression, survival, and quality of life until your disease progresses.
AI-generated summary from trial data · Jun 7, 2026 · Not medical advice
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