Plain-English translation of NCT06340945 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing ultrasound-guided thermal ablation—a procedure that uses heat to shrink benign (non-cancerous) thyroid nodules. Researchers want to see how well this treatment works for patients who have nodules causing cosmetic concerns, symptoms, or worry about growth, and who prefer not to have surgery.
Many people have benign thyroid nodules that cause no problems, but some patients experience symptoms or are concerned about how the nodules look or might change over time. Surgery is one option, but not everyone wants or can have surgery. This trial tests whether heat-based treatment can safely shrink these nodules and help patients avoid surgery.
You likely qualify if…
You likely don't qualify if…
If you join this trial, you will receive the ultrasound-guided heat treatment as an outpatient procedure. After treatment, you will have follow-up visits and ultrasound imaging to see how well your nodule responds—this continues for at least 6 months. Researchers will track how much your nodule shrinks and whether you have any improvement in symptoms or concerns.
AI-generated summary from trial data · Jun 4, 2026 · Not medical advice
China
Sponsor
Chinese PLA General Hospital
Enrollment target
~1,500 participants
Started
April 2024
Primary completion
December 2027
Age range
18 Years and older
Last updated on clinicaltrials.gov in March 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Lin Yan, MD.
Chinese PLA General Hospital
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.