Plain-English translation of NCT06341699 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study looks at two hormones—cortisol and testosterone—in men with severe obesity to understand how these hormones affect bone strength, cholesterol levels, and heart disease risk. Researchers will measure how sensitive your body is to these hormones and collect blood samples to see if hormone patterns can predict who is at higher risk for heart problems.
Many men with severe obesity have changes in their hormone levels, but doctors don't fully understand how these hormone changes connect to bone loss, heart disease, and other complications of obesity. This study aims to fill that gap so doctors can better predict and prevent these serious health problems.
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You will visit the study center for an enrollment visit where you'll complete questionnaires about your mood and symptoms, and provide information about your medical history and current health. A blood sample will be collected and analyzed at a specialized laboratory to measure your hormone levels, bone health markers, cholesterol function, and genetic factors related to hormone sensitivity. The study does not involve taking any medication—it is purely observational to help researchers understand your individual hormone profile.
AI-generated summary from trial data · Jun 5, 2026 · Not medical advice
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