Plain-English translation of NCT06345833 on ClinicalTrials.gov โ ยท Source last updated ยท Translation generated ยท How we translate trials
Read our Hemophilia research guide โPhase 1 โ Testing in a small group (usually 20โ80 people) to find a safe dose and watch for side effects.
This trial was testing tranexamic acid (TXA), a medication that helps reduce bleeding, when applied directly to the skin during facelift surgery. Researchers wanted to see if this medication could help decrease bleeding during and after the procedure, and they compared it to a placebo (salt water) applied to the other side of the face. Because each patient's two sides were treated differently, each person essentially served as their own comparison.
Although this medication has been used safely in many types of surgery for decades and is recommended by major medical organizations, it is not yet officially approved by the FDA specifically for use during facelift surgery. This trial aimed to gather evidence about whether the treatment works safely and effectively when applied locally to the face, rather than given through the bloodstream.
If you joined this trial, your facelift surgery would proceed normally, but during the procedure, one randomly chosen side of your face would receive the experimental bleeding-control medication in one of three forms (mixed with numbing medicine, soaked into gauze pads, or both), while the other side would receive salt water as a comparison. Your surgeon and the research team would then monitor and compare how much bleeding occurred on each side to see if the medication made a difference.
AI-generated summary from trial data ยท Aug 11, 2026 ยท Not medical advice
United States