Plain-English translation of NCT06348472 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This research is exploring whether certain biological markers—chemicals in your body related to stress and immune function—can help predict who will benefit most from psychotherapy for trauma and PTSD. Researchers will collect small saliva samples from people receiving therapy to measure these markers and see if they connect to how well the treatment works.
Many people with PTSD don't fully recover even after receiving therapy, and doctors don't yet have a reliable way to predict who will respond well to treatment. This study aims to find biological clues that could help personalize treatment plans and improve outcomes.
You likely qualify if…
You likely don't qualify if…
You'll attend weekly psychotherapy sessions for 12 weeks at the trauma clinic, which is standard care you'd receive anyway. Before and after your first, sixth, and twelfth sessions, you'll provide small saliva samples (collected in simple containers) for researchers to test. You'll also complete brief questionnaires about how your symptoms are improving. The whole process takes about 12 weeks.
AI-generated summary from trial data · Jun 2, 2026 · Not medical advice
Israel
Enrollment target
~100 participants
Started
March 2024
Primary completion
March 2028
Age range
18 Years – 80 Years
Last updated on clinicaltrials.gov in June 2024.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Omer Sedoff, MA
Shalvata Mental Health Center
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.