Plain-English translation of NCT06352671 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This trial is tracking patients who undergo the Ross procedure, a specialized heart valve surgery. In this procedure, your own pulmonary valve (a valve in your heart that normally controls blood flow to your lungs) is used to replace a damaged aortic valve (the valve that controls blood flow from your heart to your body). The study aims to document how well this living valve works over the long term and identify the best surgical techniques.
When the main heart valve needs replacement, doctors typically use either artificial mechanical valves (which require blood-thinning medication for life) or tissue valves from donors (which eventually wear out and need replacement). This trial exists to prove that using your own valve is a safe and durable option for people who may live 15+ more years, potentially avoiding the downsides of the other options.
You likely qualify if…
You likely don't qualify if…
If you qualify, you will undergo the Ross procedure at one of the five participating medical centers. After surgery, you will be followed as part of a long-term registry where researchers will track how your valve functions over time through regular check-ups, imaging tests, and clinical evaluations. This prospective study will help doctors understand the durability and safety of this approach so they can better counsel future patients with aortic valve disease.
AI-generated summary from trial data · Aug 24, 2026 · Not medical advice
United States
Sponsor
Baylor Research Institute
Enrollment target
~225 participants
Started
October 2023
Primary completion
December 2026
Age range
18 Years – 90 Years
Last updated on clinicaltrials.gov in April 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Bonnie Ostergren
Baylor Research Institute
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.