Testing a medication to prevent mouth sores from cancer radiation

This clinical trial is testing whether N-acetylcysteine, a medication that may protect healthy tissue, can prevent or reduce severe mouth sores (mucositis) that commonly occur during radiation therapy for head and neck cancer. About 50 patients will participate at Mansoura University Hospital in Egypt. Half will receive standard cancer care alone, while the other half will receive standard care plus this medication.

Radiation therapy for head and neck cancer often damages the delicate lining of the mouth and throat, causing painful sores that can make eating and swallowing difficult. Researchers believe this medication may protect the mouth's healthy tissue and reduce the severity of these sores, improving quality of life during cancer treatment.