Testing a diabetes medicine for fatty liver disease in teens

This research study is testing whether a medication called empagliflozin can help reduce fatty buildup in the liver of teenagers with obesity. The medication is normally used to treat diabetes, but researchers think it might also help the liver in young people who have fatty liver disease but do not yet have diabetes. Half of the participants will receive the actual medication, and half will receive a placebo (a pill with no active medicine), while all participants also receive counseling about healthy lifestyle changes.

Fatty liver disease is becoming increasingly common in teenagers with obesity, and there are currently very few treatment options. Researchers want to see if this medication could be a safe and effective way to help reduce liver fat and prevent long-term liver damage in young people.