Plain-English translation of NCT06359938 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This is an early-stage trial testing a modified pacemaker approach called respiratory sinus arrhythmia (RSA) pacing in patients with heart failure who have just undergone bypass surgery. The new pacing method mimics how your heart naturally speeds up when you breathe in and slows down when you breathe out—a pattern that gets lost in heart failure. Researchers believe restoring this natural rhythm through temporary pacing wires (which are already standard after bypass surgery) might help your heart function better over the first 10 days after surgery.
In heart failure, the heart loses this natural breathing-linked rhythm, which may contribute to poor function and complications. This trial exists to see whether restoring that rhythm through the new pacing approach is safe and whether it can actually improve how well your heart works after bypass surgery.
You likely qualify if…
You likely don't qualify if…
If you qualify and are enrolled, you will be randomly assigned to receive either the new RSA pacing or standard pacing through temporary wires that your surgeon places during your bypass surgery. Pacing will start the day after surgery (once you're off the ventilator) and continue for up to 10 days or until you're ready to go home, whichever comes first. The research team will monitor your heart rhythm and heart function during this time to check if the new pacing approach is safe and whether it helps your heart work better.
AI-generated summary from trial data · Jun 22, 2026 · Not medical advice
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