Plain-English translation of NCT06360120 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 3 — Testing in thousands of people, comparing the treatment against what doctors currently use. This is the last big step before approval.
This trial is testing whether atorvastatin or rosuvastatin — two common cholesterol medications — work better when given together with clopidogrel, a blood thinner, to patients who have had a large-vessel ischemic stroke. Researchers want to see which medication combination helps prevent future strokes and improves recovery over three months. Both are established drugs, but this study will compare their effectiveness in this specific situation.
Large-vessel strokes are serious events that can cause lasting disability. Doctors already use blood thinners and cholesterol medications to prevent future strokes, but it's unclear whether one cholesterol medication works better than another when paired with blood thinner therapy. This study aims to find the best combination to protect patients.
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You would take a daily cholesterol medication (either atorvastatin or rosuvastatin) along with a daily blood thinner (clopidogrel) for three months. You would have clinic visits and brain imaging scans (CT or MRI) to assess your stroke, and your recovery would be checked at one week and again at three months. Blood tests would also be done regularly to monitor how the medications are working and ensure your liver and cholesterol levels are safe.
AI-generated summary from trial data · Jul 13, 2026 · Not medical advice
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