Plain-English translation of NCT06361160 on ClinicalTrials.gov ↗ · Source last updated · Translation generated ·
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing a new approach using transcranial magnetic stimulation (TMS) — a non-invasive brain stimulation technique — to reduce auditory-verbal hallucinations (hearing voices) in people with treatment-resistant schizophrenia. Researchers want to see if applying magnetic pulses to specific areas of the brain when someone is experiencing hallucinations can interrupt or reduce them. This treatment builds toward developing a future 'closed-loop' system that would automatically detect when voices are occurring and deliver brain stimulation in real time.
About one-third of people with schizophrenia develop a form that doesn't respond well to current antipsychotic medications, and many of these individuals continue to hear voices despite treatment. This trial exists to test whether targeted brain stimulation can provide relief when medication alone isn't working.
You would attend 12 weekly sessions over three months. During these sessions, you'll receive magnetic brain stimulation while describing any voices you're hearing — some sessions will use active stimulation and some will be sham (fake) stimulation, and neither you nor the researchers will know which is which during phase 1. After completing phase 1, you'd have the option to continue with phase 2, which offers a more intensive treatment protocol of 10 sessions of proven brain stimulation delivered over one week.
AI-generated summary from trial data · Jun 11, 2026 · Not medical advice
France