Recruiting

Building Physical Activity Habits to Prevent Memory Loss in Older Hispanic Adults

Plain-English translation of NCT06362824 on ClinicalTrials.gov ↗ · Source last updated July 2026 · Translation generated June 2026 · How we translate trials

This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.

What is this trial?

This study is testing whether a program called De Pie — designed specifically for Hispanic and Latino older adults — can help people become more physically active and protect their brain health. Researchers will compare De Pie to an active comparison program that teaches general brain health topics. The goal is to see if increasing physical activity can help reduce the risk of Alzheimer's disease and related memory problems, which affect Hispanic and Latino communities at higher rates than other groups.

Hispanic and Latino older adults face higher rates of Alzheimer's disease and memory loss, yet there are very few programs designed with their culture, language, and needs in mind. This study exists to create and test a physical activity program that works for this community and could help prevent dementia.

Do you qualify?

You likely qualify if…

you are between 55 and 89 years old
you identify as Hispanic or Latino(a)
you can walk at least one block without help
you are able to participate for up to 20 weeks and take phone calls weekdays between 8am–5pm
you speak and read Spanish or English, and have a smartphone
you are willing to wear a small activity tracker for up to 2 weeks, twice during the study

You likely don't qualify if…

you have signs of memory loss or dementia on the screening test
you have had a heart attack, irregular heartbeat, or recent fall requiring hospitalization
you have been diagnosed with cancer requiring treatment in the past year (except skin cancer)
your doctor has recently advised you to avoid physical activity
you are unable to hear phone conversations, even with a hearing aid, or unable to get an email address

What participation looks like

If you join, you will be randomly assigned to either the De Pie program or the comparison program for 12 weeks. In De Pie, you'll learn how to reduce sitting time and gradually add structured exercise with help from health coaches. In the comparison program, you'll receive one introductory phone call and then work through 10 modules about brain health topics like diet and sleep. Throughout the study, you'll wear a small activity tracker twice, complete surveys, and stay in touch with the research team by phone. The entire study lasts about 20 weeks.

AI-generated summary from trial data · Jun 10, 2026 · Not medical advice

Trial locations(2 sites)

United States

University of California San Diego, San Diego, California

Kaiser Permanente Washington, Seattle, Washington