Plain-English translation of NCT06363253 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Obesity research guide →Researchers are studying how the trillions of bacteria, viruses, and other microorganisms living in your body—especially in your gut—may influence obesity, muscle loss, and long-term inflammation. This pilot study will compare samples from people with obesity, people with age-related muscle weakness, and healthy volunteers to identify patterns that might help doctors personalize treatment in the future.
Right now, doctors don't fully understand why some people develop obesity or lose muscle mass as they age, and treatments are often one-size-fits-all. This research aims to uncover whether changes in gut bacteria and the chemicals they produce play a role in these conditions, which could eventually lead to more personalized care.
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You will visit the study site to provide multiple samples: stool, saliva, blood, urine, and a small mouth swab. The researchers will test these samples to identify the bacteria, viruses, and chemical signatures in your body. You may also have your grip strength, walking speed, and muscle mass measured. The study is observational, meaning you won't take a medication—you're simply allowing researchers to study your samples to look for patterns.
AI-generated summary from trial data · Jun 5, 2026 · Not medical advice
Singapore
Collaborators
Singapore General Hospital, Nanyang Technological University
Enrollment target
~600 participants
Started
August 2023
Primary completion
December 2026
Age range
21 Years – 99 Years
Last updated on clinicaltrials.gov in May 2025.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Koy Min Chue
Sengkang General Hospital
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.