Plain-English translation of NCT06363305 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing whether capsaicin—a natural compound found in hot peppers—can help improve blood pressure and blood vessel health. The researchers want to understand whether this supplement works differently in men and women. You would take either capsaicin capsules or a placebo (inactive) capsule daily for 6 weeks while the research team measures your blood pressure and heart health.
High blood pressure affects millions of people, and many are looking for natural ways to help manage it. This medication has shown promise in early research, but scientists need to understand whether it works the same way for everyone—or if sex makes a difference in how effective it is.
You would visit the research site to have your baseline blood pressure, blood vessel function, and heart rate measured. Then you would take either the capsaicin capsules or placebo capsules twice daily at home for 6 weeks. At the end, you would return for follow-up measurements to see if anything changed. The researchers will also ask you to provide urine samples to track how your body processes the supplement.
AI-generated summary from trial data · Jun 5, 2026 · Not medical advice
United States
Skidmore College
Collaborators
American Heart Association
Enrollment target
~80 participants
Started
July 2024
Primary completion
December 2025
Age range
18 Years and older
Last updated on clinicaltrials.gov in July 2024.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Stephen Ives, PhD
Skidmore College