Plain-English translation of NCT06365359 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Researchers want to understand how exposure to chlordecone, a pesticide that was widely used on banana farms in Martinique decades ago, might affect lupus disease in people living in that region. This is the first human study to explore this connection — earlier animal research suggests the pesticide could make lupus worse or change how the immune system behaves.
Many people in Martinique have been exposed to chlordecone through contaminated food and water, and lupus is a serious autoimmune disease that can cause severe kidney damage. Researchers need to know whether this pesticide exposure is making lupus worse in patients so they can better protect and treat people in the region.
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As a participant, you would allow researchers to access your medical records from the Martinique University Hospital and potentially provide blood samples to measure pesticide exposure and lupus disease activity markers. The study will collect information about your lupus history, kidney function, and current symptoms over time to see if there is a connection between chlordecone exposure and your disease severity.
AI-generated summary from trial data · Jun 5, 2026 · Not medical advice
France