Using AI to detect endometrial cancer from ultrasound scans

This research study is testing an artificial intelligence tool that analyzes ultrasound images of the uterus (endometrium) to help identify women with endometrial cancer or precancerous changes. Researchers at Mayo Clinic want to see if this AI tool can accurately spot concerning findings in women who have had vaginal bleeding after menopause. The study will compare the AI tool's results to actual tissue biopsies to see how well it works.

Currently, women with postmenopausal bleeding need biopsies (tissue samples) to find out if they have cancer or precancerous changes—a procedure that can be uncomfortable and risky. This trial aims to develop a non-invasive way using AI and ultrasound images to identify which women actually need a biopsy, potentially sparing many women from unnecessary procedures.