Plain-English translation of NCT06366347 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 2 — Testing in a bigger group (up to a few hundred people) to see if the treatment actually works and is still safe.
This trial is testing whether two medications called and , given together as a maintenance therapy (ongoing treatment after initial chemotherapy), can help keep advanced or recurrent endometrial cancer under control. Both drugs have been used to treat other types of cancer, but this study will be the first to see if they work together for endometrial cancer in this specific patient population.
Endometrial cancer that has spread or come back is hard to treat, and patients need better long-term options after their initial chemotherapy. This study is exploring whether continuing this medication combination can slow cancer growth and help patients live longer.
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You will take two pills by mouth daily for up to 2 years— twice daily and once daily, in 21-day cycles. You'll have regular clinic visits with blood work, and imaging scans (CT, MRI, or PET) every 9 weeks for the first 9 months, then every 12 months after that. After you stop the medication, you'll be followed for an additional 3 years with periodic check-ups to see how you're doing.
AI-generated summary from trial data · Jun 10, 2026 · Not medical advice
United States