Plain-English translation of NCT06367725 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This is an observational study that tracks how dexamethasone, a steroid medication commonly used to treat childhood acute lymphoblastic leukemia, moves through your body and affects your health. Researchers want to understand how much of the medication reaches your bloodstream and brain fluid, whether it helps fight the leukemia in the brain, and whether it affects bone strength or causes nerve-related side effects.
Dexamethasone is an important part of treating childhood leukemia, but doctors don't fully understand how different doses affect different children, or how it impacts bones and the nervous system. This study will help doctors personalize treatment and better predict which children might need extra support to protect their bones and brain health.
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You will continue receiving your regular leukemia treatment as planned. The study involves giving extra blood samples through your existing treatment line, and collecting a small amount of spinal fluid during your routine lumbar punctures. You'll visit the clinic four times for bone density scans (starting treatment, 6 months later, one month after finishing, and one year later) and complete questionnaires about how you're feeling and your daily activity level.
AI-generated summary from trial data · Jun 30, 2026 · Not medical advice
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