Plain-English translation of NCT06368648 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Researchers are testing a device called CoMind One EFS that can measure brain pressure without surgery. Right now, doctors monitor brain pressure using invasive catheters placed inside the brain, which carries risks. This study compares the new non-invasive device's measurements against the standard invasive monitors to see if it can reliably estimate brain pressure and how the brain regulates blood flow.
High pressure inside the brain is dangerous and occurs after traumatic brain injuries, strokes, and other neurological emergencies. Doctors currently must place invasive catheters into the brain to monitor this pressure, which carries infection and injury risks. This trial aims to develop a safer, non-invasive way to measure brain pressure that could eventually replace the need for these risky invasive procedures.
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While you receive your standard invasive brain pressure and blood pressure monitoring in the hospital, researchers will place a non-invasive sensor device on your forehead. The device will record measurements at the same time your standard invasive monitors are recording. You will not need additional procedures—the device simply sits on your skin and collects data alongside your normal care.
AI-generated summary from trial data · Jun 16, 2026 · Not medical advice
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